Inclusion Criteria:

- adult patients, <=75 years of age;

- single organ recipients of renal allograft;

- negative pregnancy test for women of childbearing potential; reliable contraception
must be used before starting drug therapy, until 6 weeks after the last dose of study
medication.

Exclusion Criteria:

- severe gastrointestinal disease which may influence the absorption of oral drug
therapy;

- severe infection, HIV or active hepatitis;

- active gastric ulcers;

- malignancy other than cured skin cancer;

- severe anemia, leucopenia or thrombocytopenia.