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HPV Infections in Older Women

25 Years
65 Years
Open (Enrolling)
Papillomavirus Infections

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Trial Information

HPV Infections in Older Women

Whether older women are susceptible to acquiring new, persistent high-risk (HR) HPV
infections from new sex partners is largely unknown. This is a longitudinal study of
predictors of HR HPV infections in two populations of women aged 25 to 44 and 45 to 65 who
have used internet dating websites in the past year. 300 women will be recruited and mailed
kits for self-collecting vaginal specimens for HPV DNA testing. Women will self-collect four
sets of vaginal specimens four months apart, and complete sexual behavior questionnaires at
the time of each self-collection. We will identify behavioral and health predictors of
type-specific HR HPV infections, predictors of repeatedly-detected HR HPV infections, and
evaluate study participants' experiences with self-collecting vaginal specimens and
attitudes towards HPV vaccination and cervical cancer screening. This information is
important for developing guidelines for HPV vaccine implementation and cervical cancer
screening guidelines in populations of older women.

Inclusion Criteria:

- Have had sex with men

- Have used the internet to search for romantic partners in the past year (e.g. posted
or responded to an ad on an internet dating website or social networking website)

Exclusion Criteria:

- Pregnant, breastfeeding, or planning a pregnancy in the next 6 months

- Hysterectomy

Type of Study:


Study Design:

Observational Model: Cohort, Time Perspective: Prospective

Outcome Measure:

High-risk HPV DNA

Outcome Time Frame:

Every 4 months for 1 year

Safety Issue:


Principal Investigator

Rachel L Winer, PhD

Investigator Role:

Principal Investigator

Investigator Affiliation:

University of Washington


United States: Institutional Review Board

Study ID:




Start Date:

July 2008

Completion Date:

June 2012

Related Keywords:

  • Papillomavirus Infections
  • Papillomavirus Infections



University of WashingtonSeattle, Washington  98195