A Quality of Life Study for Patients With Primary or Metastatic Liver Cancer Who Are Treated With Radioembolization (Y90 Microspheres) or Transcatheter Arterial Embolization (TACE)
18 Years
N/A
Both
Liver Cancer, Metastatic Cancer
Trial Information
A Quality of Life Study for Patients With Primary or Metastatic Liver Cancer Who Are Treated With Radioembolization (Y90 Microspheres) or Transcatheter Arterial Embolization (TACE)
OBJECTIVES:
Primary
- Assess the quality of life (QOL) as defined by the presence or absence of physical,
social, emotional, and functional distress in patients with primary or metastatic liver
cancer undergoing treatment with radioembolization or transcatheter arterial
embolization.
- Compare the time course of QOL measures between treatment groups in patients treated
with these regimens.
- Compare the time course of QOL measures between patient subgroups defined by
pre-treatment quality of life or tumor burden.
OUTLINE: Patients complete FACT-Hep version 4 surveys on quality of life prior to initiation
of embolization, and at 2 weeks and 1 month after completion of embolization.
Inclusion Criteria
DISEASE CHARACTERISTICS:
- Diagnosis of primary hepatocellular cancer or metastatic liver cancer
- Planning radioembolization or transcatheter arterial embolization using yttrium Y 90
glass microspheres
- No encephalopathy
PATIENT CHARACTERISTICS:
- ECOG performance status 0-2
- Bilirubin ≤ 3 mg/dL
- Able to comply with study procedures
PRIOR CONCURRENT THERAPY:
- No prior treatment with radioembolization or transcatheter arterial embolization
Type of Study:
Observational
Study Design:
Observational Model: Cohort, Time Perspective: Prospective
Outcome Measure:
Quality of life of all patients over the course of treatment
Outcome Time Frame:
Before treatment, 2 weeks post, and 1 month post
Safety Issue:
No
Principal Investigator
Peggy Gilbertsen, RN, BS
Investigator Role:
Principal Investigator
Investigator Affiliation:
Robert H. Lurie Cancer Center
Authority:
United States: Institutional Review Board
Study ID:
NU 07Q1
NCT ID:
NCT00739167
Start Date:
April 2008
Completion Date:
May 2010
Related Keywords:
- Liver Cancer
- Metastatic Cancer
- adult primary hepatocellular carcinoma
- advanced adult primary liver cancer
- liver metastases
- recurrent adult primary liver cancer
- Liver Neoplasms
- Neoplasm Metastasis
- Neoplasms
- Neoplasms, Second Primary
Name | Location |
|---|---|
| Robert H. Lurie Comprehensive Cancer Center at Northwestern University | Chicago, Illinois 60611 |
