Improving the Pregnancy Rate With Endometrial Sampling Before Intrauterine Insemination
Endometrial sampling is performed using the standard technique in the outpatient department.
Similarly, superovulation with gonadotrophins will be performed according to our standard
practice.Endometrial sampling will be done in the follicular phase not later than day 10 of
the cycle. Endometrial sampling will be performed using Pipelle sampling catheter. The
Pipelle is inserted gently through the cervical canal into the uterine cavity and advanced
slowly till just resistance felt by the operator. Then, the piston is withdrawn to create
negative suction and gentle movement of Pipelle up and down in the uterine cavity is
performed while it is against the uterine wall. The Pipelle catheter is withdrawn gently and
any obtained specimen will be sent for histopathological examination.
Allocation: Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
The rate of clinical pregnancy
Togas Tulandi, MD, MHCM
McGill University Health Center
Canada: Ethics Review Committee