Trial Information
Awareness and Attitudes Regarding Prenatal and Preimplantation Genetic Diagnosis for Inherited Breast/Ovarian Cancer Risk
Inclusion Criteria:
- Females and males who are carriers of deleterious mutations in the genes BRCA1 or
BRCA2.
- Over age 18 and:
1. For women, less than 43
2. For men, less than 50.
- Received genetic testing and counseling for BRCA.
- Fluent in English.
Exclusion Criteria:
- Patients who are currently under treatment (chemotherapy, radiation)
- Individuals who refuse to discuss reproductive issues.
- Unable to give informed consent due to physical, cognitive, or psychiatric disability
Type of Study:
Observational
Study Design:
Observational Model: Cohort, Time Perspective: Prospective
Outcome Measure:
To explore the attitudes of BRCA1/2 mutation carriers about PGD/PND, most notably benefits and drawbacks, as well as ethical and emotional considerations;
Outcome Time Frame:
conclusion of study
Safety Issue:
No
Principal Investigator
Karen Hurley, PhD
Investigator Role:
Principal Investigator
Investigator Affiliation:
Memorial Sloan-Kettering Cancer Center
Authority:
United States: Institutional Review Board
Study ID:
06-137
NCT ID:
NCT00735150
Start Date:
March 2008
Completion Date:
October 2010
Related Keywords:
- Breast Cancer
- Ovarian Cancer
- Breast
- Ovary
- Mutation carrier
- Breast Neoplasms
- Ovarian Neoplasms
Name | Location |
Memorial Sloan-Kettering Cancer Center |
New York, New York 10021 |