Optical Coherence Tomography of Human Airways
- Correlate optical coherence tomography images of the airway with airway histology.
- Develop an imaging technique to detect premalignant airway epithelial changes
(carcinoma in situ, dysplasia) to study the transformation process as well as intervene
and prevent the development of lung cancer.
OUTLINE: Bronchoscopic imaging and optical coherence tomography are performed on lung tissue
samples collected during surgery. All imaged areas are marked. The marked areas are then
excised and fixed in formalin for histopathologic analysis.
Observational Model: Case-Only, Time Perspective: Retrospective
Correlation of optical coherence tomography images of the airway with airway histology
This study will involve discarded tissue from 10 subjects with pathology specimens over one year.
Rana Hejal, MD
Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center
United States: Institutional Review Board
|Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center||Cleveland, Ohio 44106-5065|