Surgical Treatment of Hilar Cholangiocarcinoma: Minor or Major Liver Resection?
Objective: To determine the safety and efficacy of minor and major hepatectomy selected by
predetermined criteria in patients with hilar cholangiocarcinoma (HC).
Summary Background Data: For HC treated with hepatectomy, the extent of liver resection
remains controversial despite extensive studies.
Methods: From January 2000 to December 2007, we prospectively studied patients who received
surgical treatment for HC. Of the 187 patients who were surgically treated, 138 (73.8%)
underwent resection with a curative intent. Minor hepatectomy was carried out in 93 patients
who had Bismuth-Corlette types I, II and III HC without hepatic artery/portal vein invasion;
and major hepatectomy in 45 patients who had type III HC with hepatic artery/portal vein
invasion, or type IV HC.
On multivariate analysis, prognostic factors significantly impacted on long-term survival were UICC tumor stage and histopathologic grade.
China: Food and Drug Administration