Management of Cervical Intraepithelial Neoplasia Grade 2
Pap smear and colposcopy were performed at every follow-up visit and all lesions were
completely visible at colposcopy.
The researchers purpose was to make some comments about the over treatment and the
misclassification of CIN 2.
Interventional
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
43 women in the follow-up group, 44.1% experienced spontaneous regression, 20.9% had partial regression, 23.2% progressed to CIN3, and 11.6% showed persistence. 44 women whose lesion was excised, the regression rate was 90.9%
12 months
Yes
Sylvia F Brenna, MD, PhD
Principal Investigator
Universidade Cidade de Sao Paulo
Brazil: Ethics Committee
CIN 2
NCT00733109
March 2003
July 2007
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