Inclusion Criteria:

- patients with hepatocellular,confirmed by pathological examination

- patients with a live function test showed Child A or B

- Indocyanine green test showed less than 30％ after 15min,and the patients showed a
tolerance of RFA and TACE

- Tumor stage is early period(according to Milan Standard),that is,the diameter of
single node should be less than 5cm；the node of tumor should be less than 3 and the
diameter less than 3cm.

- without metastasis in lymphnode or other organs

- written consent inform assigned

Exclusion Criteria:

- preoperative examination showed malignant thrombosis in the first class branch of
portal vein or hepatic vein or vena cava

- metastatic cancer of liver

- patients with a poor tolerance of RFA and TACE

- patients received other therapies.