Presurgical Planning With Motion Corrected fMRI Mapping of Motor Cortex in Patients With Cerebral Tumors
N/A
N/A
Both
Brain Tumors
Trial Information
Presurgical Planning With Motion Corrected fMRI Mapping of Motor Cortex in Patients With Cerebral Tumors
The purpose of this study is to determine if fMRI is precise enough to be used in
preoperative decision making for patients who have brain tumors. Before a patient has brain
surgery to have the tumor removed, functional mapping of the brain takes place either
intra-operatively or post operatively after a subdural grid implant has been placed.
Mapping helps the surgeon determine which areas of the brain are responsible for different
important body functions. During this mapping procedure the surgeon determines if they can
safely remove all or part of a brain tumor. The investigators are hoping to show that fMRI
is just as accurate in mapping out different areas of the brain, without having to utilize
an invasive form of brain mapping.
Inclusion Criteria:
- All patients with brain tumors and healthy volunteers
Exclusion Criteria:
- If patients are pregnant.
- If patients suffer from a significant degree of claustrophobia.
- If patients are claustrophobic and requires general anesthesia to complete the
diagnostic MRI.
- Contraindications for an MRI due to surgeries and/or implantation of pacemakers or
pacemaker wires, open heart surgery for placement of an artificial heart valve, brain
aneurysm surgery, middle ear implants, hearing aids, braces or extensive dental work,
cataract surgery or lens implant, any implanted mechanical or electrical device,
implanted neurological stimulators or artificial limbs or joints.
- Contraindications from an MRI due to foreign metallic objects in the body such as:
bullets, BBs, pellets, surgical magnetic metal clips, joint or bone pins, metal
plates, shrapnel or any one who has a history of working near metal who could have
metal shavings in their eyes.
Type of Study:
Interventional
Study Design:
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
Outcome Measure:
Determining whether fMRI mapping is as effective as invasive presurgical mapping.
Outcome Time Frame:
Time of procedure.
Safety Issue:
No
Principal Investigator
Boklye Kim, M.D.
Investigator Role:
Principal Investigator
Investigator Affiliation:
University of Michigan
Authority:
United States: Institutional Review Board
Study ID:
1999-0643
NCT ID:
NCT00724737
Start Date:
July 2006
Completion Date:
August 2011
Related Keywords:
- Brain Tumors
- Brain Neoplasms
Name | Location |
|---|---|
| University of Michigan Health System | Ann Arbor, Michigan |
