Inclusion Criteria:

- Metastatic epithelial cancer

- Above 18 years of age

- Failure of at least one chemotherapy protocol

- Clinical performance status of ECOG 0,1

- Absolute neutrophil count greater than 1000/mm3

- Serum ALT/AST less than three times the upper limit of normal

- Serum creatinine less than or equal to 1.6 mg/dl.

- Must be able to understand and sign the Informed Consent document

Exclusion Criteria:

- Below 18 years of age

- Women who are pregnant

- Life expectancy of less than three months