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The Impact of Electrocoagulation on Ovarian Reserve After Laparoscopic Exc

Phase 4
18 Years
40 Years
Not Enrolling
Ovarian Cysts

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Trial Information

The Impact of Electrocoagulation on Ovarian Reserve After Laparoscopic Exc

Laparoscopic cystectomy is currently considered the treatment of choice in women with benign
ovarian cysts and has gained increasing acceptance among gynecological surgeons(1). However,
the safety of this technique in terms of ovarian damage to the operated gonad has recently
been questioned. In the present study, with the combined use of serum hormonal evaluation
and ultrasound examination, we planned to prospectively investigate the ovarian reserve
after the excision of benign ovarian cysts. The damage to ovarian reserve will be evaluated
through a 12-months follow-up after the application of bipolar, ultrasonic scalpel
electrocoagulation or suture during ovarian cystectomy

Inclusion Criteria

Inclusion criteria:

- Age 18-40 years

- Uni/bilateral ovarian cyst(s) without clinical and sonographic suspicion of ovarian

- Regular menstrual cycles defined as cycle length between 25 and 35 days in the 6
months before surgery

- Agreement to be enrolled in the study

Exclusion criteria:

- Prior ovarian surgery

- Surgical necessity to perform adnexectomy

- Known endocrine disease

- Post operative pathologic diagnosis was not benign ovarian cyst

- Oral contraceptive use before surgery

Type of Study:


Study Design:

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Supportive Care

Outcome Measure:

Serum FSH and E2 assays

Outcome Time Frame:

12 months

Safety Issue:


Principal Investigator

changzhong li, M.D.

Investigator Role:

Study Director

Investigator Affiliation:

Shandong Provincial Hospital


China: Ministry of Health

Study ID:




Start Date:

November 2003

Completion Date:

May 2008

Related Keywords:

  • Ovarian Cysts
  • Ovarian Cysts
  • Electrocoagulation
  • Ovarian Function Tests
  • Laparoscopy
  • Cysts
  • Ovarian Cysts