Positron Emission Tomography Study in Patients With Non-Hodgkin Lymphoma
N/A
N/A
Both
Lymphoma
Trial Information
Positron Emission Tomography Study in Patients With Non-Hodgkin Lymphoma
OBJECTIVES:
- To determine if a fluorine 18-fludeoxyglucose positron emission tomography scan,
performed as early as day 30 after high-dose chemotherapy and autologous stem cell
transplantation, may be useful in identifying patients with non-Hodgkin lymphoma who
may benefit from early interventions, including reduced intensity stem cell
transplantation or additional therapy, to preempt disease relapse and improve overall
survival.
OUTLINE: Conventional imaging, biopsy, and clinical examination findings are reviewed to
determine patient clinical outcome (e.g., complete remission, disease progression/relapse,
or death related to the primary disease).
Inclusion Criteria:
DISEASE CHARACTERISTICS:
- Diagnosis of non-Hodgkin lymphoma
- Has undergone high-dose chemotherapy followed by autologous stem cell transplantation
at Vanderbilt University between March 1997 and August 2005
- Has undergone fluorine 18-fludeoxyglucose PET within 70 days prior to and/or at
approximately 30 days and 100 days after high-dose chemotherapy and autologous
stem cell transplantation
Exclusion Criteria:
PATIENT CHARACTERISTICS:
- Not specified
PRIOR CONCURRENT THERAPY:
- See Disease Characteristics
Type of Study:
Observational
Study Design:
Observational Model: Cohort, Time Perspective: Retrospective
Outcome Measure:
Correlation of sensitivity, specificity, positive predictive value, and negative predictive value of fluorine 18-fludeoxyglucose positron emission tomography scan with with patients' clinical outcomes.
Outcome Time Frame:
from the date of stem cell transplant to date of clinical disease progression or to date of last follow-up
Safety Issue:
No
Principal Investigator
Adetola A. Kassim, MD
Investigator Role:
Principal Investigator
Investigator Affiliation:
Vanderbilt-Ingram Cancer Center
Authority:
United States: Federal Government
Study ID:
VICC BMT 0828
NCT ID:
NCT00712556
Start Date:
May 2008
Completion Date:
March 2009
Related Keywords:
- Lymphoma
- stage III adult Burkitt lymphoma
- stage III adult diffuse large cell lymphoma
- stage III adult diffuse mixed cell lymphoma
- stage III adult diffuse small cleaved cell lymphoma
- stage III adult immunoblastic large cell lymphoma
- stage III adult lymphoblastic lymphoma
- stage III grade 1 follicular lymphoma
- stage III grade 2 follicular lymphoma
- stage III grade 3 follicular lymphoma
- stage III mantle cell lymphoma
- stage III marginal zone lymphoma
- stage III small lymphocytic lymphoma
- stage IV adult Burkitt lymphoma
- stage IV adult diffuse large cell lymphoma
- stage IV adult diffuse mixed cell lymphoma
- stage IV adult diffuse small cleaved cell lymphoma
- stage IV adult immunoblastic large cell lymphoma
- stage IV adult lymphoblastic lymphoma
- stage IV grade 1 follicular lymphoma
- stage IV grade 2 follicular lymphoma
- stage IV grade 3 follicular lymphoma
- stage IV mantle cell lymphoma
- stage IV marginal zone lymphoma
- stage IV small lymphocytic lymphoma
- recurrent adult Burkitt lymphoma
- recurrent adult diffuse large cell lymphoma
- recurrent adult diffuse mixed cell lymphoma
- recurrent adult diffuse small cleaved cell lymphoma
- recurrent adult immunoblastic large cell lymphoma
- recurrent adult lymphoblastic lymphoma
- recurrent childhood large cell lymphoma
- recurrent childhood lymphoblastic lymphoma
- recurrent childhood small noncleaved cell lymphoma
- recurrent cutaneous T-cell non-Hodgkin lymphoma
- recurrent grade 1 follicular lymphoma
- recurrent grade 2 follicular lymphoma
- recurrent grade 3 follicular lymphoma
- recurrent mantle cell lymphoma
- recurrent marginal zone lymphoma
- recurrent small lymphocytic lymphoma
- recurrent mycosis fungoides/Sezary syndrome
- nodal marginal zone B-cell lymphoma
- splenic marginal zone lymphoma
- NC stage II adult immunoblastic large cell lymphoma
- NC stage II adult lymphoblastic lymphoma
- NC stage II grade 1 follicular lymphoma
- NC stage II grade 2 follicular lymphoma
- NC stage II grade 3 follicular lymphoma
- NC stage II mantle cell lymphoma
- NC stage II marginal zone lymphoma
- NC stage II small lymphocytic lymphoma
- Lymphoma
- Lymphoma, Non-Hodgkin
- Lymphoma, Large-Cell, Immunoblastic
Name | Location |
|---|---|
| Vanderbilt-Ingram Cancer Center | Nashville, Tennessee 37232-6838 |
| Vanderbilt-Ingram Cancer Center - Cool Springs | Nashville, Tennessee 37064 |
| Vanderbilt-Ingram Cancer Center at Franklin | Nashville, Tennessee 37064 |
