Predicting Weight Loss in People With Cancer: Development of a Screening Tool
- To identify people with cancer who are at greatest risk of future weight loss by the
development of a simple and practical screening tool.
- To estimate the reliability of the Appetite and Symptom Questionnaire (part 1).
- To develop a screening tool based on the ability of the optimal combination of items
from the three measures (ASQ, MUST, CRP) to predict clinically significant weight loss
over three months (part 2).
- To estimate the sensitivity and specificity at various cut-points of the developed
screening tool in predicting clinically significant weight loss (> 10% weight loss or
between 5% and 10% weight loss with a BMI < 20 kg/m^2) over three months (part 2).
OUTLINE: This is a two-part study.
- Part 1: Patients are asked to complete the Appetite and Symptom Questionnaire (ASQ) on
two occasions, one week apart.
- Part 2: Patients are screened at baseline for risk of malnutrition using the
Malnutrition Universal Screening Tool. Blood samples are also taken at this time to
establish the level of C-reactive protein and patients complete the ASQ. Patients are
weighed using calibrated scales and height measurements are obtained. Patients are
asked about unplanned weight loss over the previous 3-6 months. Patients are weighed
again at 3 months. Percentage weight loss is calculated at 3 months.
Primary Purpose: Supportive Care
Percentage weight loss by measuring height and weight at baseline and at 3 months
Vanessa Halliday, MSC
University of Nottingham
United States: Federal Government