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Cardiac Function and Cardiovascular Risk Profile in Testicular Cancer Patients


N/A
18 Years
N/A
Open (Enrolling)
Male
Testicular Cancer, Seminoma, Non-seminomatous

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Trial Information

Cardiac Function and Cardiovascular Risk Profile in Testicular Cancer Patients


The aim of this pilot study is to examine global and regional LV systolic and diastolic
function, cardiac output, cardiac reserve, VO2peak and CVD risk profile in males recently
diagnosed with testicular cancer treated with surgery alone or surgery and chemotherapy.


Inclusion Criteria:



- surgery and surveillance

- surgery and multi-cycle chemotherapy

- both good and intermediate prognosis seminoma and non-seminomatous germ cell
testicular tumors

- Karnofsky performance index > 70%

- no contraindications to cardiopulmonary testing

Exclusion Criteria:

- documented cardiovascular disease or evidence of myocardial ischemia on the
incremental exercise (VO2peak) test.

Type of Study:

Observational

Study Design:

Observational Model: Case Control, Time Perspective: Prospective

Principal Investigator

Mark Haykowsky, PhD

Investigator Role:

Principal Investigator

Investigator Affiliation:

University of Alberta

Authority:

Canada: Health Canada

Study ID:

GU-24167

NCT ID:

NCT00705094

Start Date:

September 2008

Completion Date:

July 2012

Related Keywords:

  • Testicular Cancer
  • Seminoma
  • Non-seminomatous
  • cardiovascular risk factors
  • cardiac function
  • VO2peak
  • Chemotherapy
  • Seminoma
  • Testicular Neoplasms

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