Genital Drop Technique With Intensity-Modulated Radiation Therapy (IMRT) in Male Anal and Distal Rectal Cancer Patients: A Dosimetric Comparison
This is a study of two different setups when treating a patient with standard of care
radiation doses. The study compares two patient setups (Standard Prone vs. Genital Drop
Technique) with identical radiation treatment technique and parameters. After the two setups
have been planned, the treating faculty reviews the setups and will choose the setup he
feels that will give the patient improved dosimetry to the local regions and hopefully
reduce toxicity and improve treatment tolerability.
Patients will not be randomized or stratified by demographic or disease risk assessment, but
treatment will be tailored to stage specific current standards of care.
An extra (non standard of care) CT is required to analyze the data.
Observational Model: Case-Only, Time Perspective: Retrospective
The Genital Drop Technique (IMRT-GD) decreased the radiation dose to the testicles scrotal skin and penile shaft compared to standard prone technique.
The Genital Drop Technique (IMRT-GD) decreased the radiation dose to the testicles, scrotal skin and penile shaft compared to the standard conformal radiation therapy (CRT) and IMRT plans while preserving adequate planned target volume (PTV) dose coverage and homogeneity to the target organs in male anal cancer patients.
Day 1. Pretreatment analysis.
Grant R. Seeger, MD
The University of Texas Medical Branch at Galveston
United States: Institutional Review Board
|The University of Texas Medical Branch at Galveston||Galveston, Texas 77550|