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Retrospective-Prospective Cohort Study Effectiveness of Comprehensive Therapy of TCM to Relieving the Risk of Recurrence and Metastasis for Stage II & III Colorectal Cancer Based on Conventional Western Medicine Therapy


N/A
18 Years
75 Years
Open (Enrolling)
Both
Colorectal Cancer

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Trial Information

Retrospective-Prospective Cohort Study Effectiveness of Comprehensive Therapy of TCM to Relieving the Risk of Recurrence and Metastasis for Stage II & III Colorectal Cancer Based on Conventional Western Medicine Therapy


CTTCM: taking TCM decoction based on syndrome differentiation daily and each dosage is
decocted two times for intervention one year with a Chinese patent medicine at least.

CWMT: with or without chemotherapy/or radiotherapy after the radical operation (R0)
(according to the latest NCCN clinical guideline).


Inclusion Criteria:



- Patient who is diagnosed colorectal cancer by patho& cytologic diagnosis since
accepting radical operation within half a year.

- Stage II or III colorectal cancer.

- 18-75 yr.

- Being able to participate and sign the informed consent.

Exclusion Criteria:

- Pregnant woman, Psychotic.

- Patient who put together with other cancer.

- Existed serious complaint and functional disturbance (impairment) with non-tumorous
in arch-organ.

- Reactiveness cerebrovascular disease (CVD) .

- Uncontrolled infection and metabolic disease.

- One item of tumor marks is progressed, and it still is progressed when patient
recheck.

- Tumor that it is neo-occurred in each organ or pelvic cavity or abdominal cavity
without definite patho-quality.

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Prospective

Outcome Measure:

The recurrence and metastasis rates for 1、2、3、4 and 5-year.

Outcome Time Frame:

one year

Safety Issue:

Yes

Principal Investigator

Yang Yufei, doctor

Investigator Role:

Study Director

Investigator Affiliation:

Xi-Yuan Hospital, China Academy of Chinese Medical Sciences, China

Authority:

China: Ethics Committee

Study ID:

WJB730603

NCT ID:

NCT00689364

Start Date:

April 2007

Completion Date:

March 2014

Related Keywords:

  • Colorectal Cancer
  • Cohort Study
  • Colorectal Cancer
  • Traditional Chinese Medicine
  • Risk of recurrence and metastasis
  • Colorectal Neoplasms
  • Neoplasm Metastasis
  • Recurrence

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