A Randomized Endoscopist-blinded Clinical Trial Comparing the Bowel Cleansing Effect and Patient Tolerability of Same Day Polyethylene Glycol Bowel Preparation Regimen v Regimen Given on the Day Before Colonoscopy
Two bowel preparation regimens of Polyethylene Glycol (PEG), commonly referred to as
"Golytely" will be tested for their efficacy (bowel cleansing effect) and patient
tolerability. The goal is to reduce the failure rates of afternoon colonoscopies, for which,
one of the main reasons attributed is inadequate bowel preparation. For the afternoon
colonoscopies, the conventional PEG regimen given on the evening prior to the day of the
colonoscopy will be compared with the novel PEG regimen given on the morning of the day of
the colonoscopy. The comparison will be drawn for two measures - bowel cleansing effect
measured from the questionnaire given to the gastroenterologists performing the colonoscopy
and the patient tolerability evaluated from the information gathered from the patient's
questionnaire.
Interventional
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Caregiver), Primary Purpose: Treatment
Bowel cleansing effect as measured by the Ottawa scale: Evening v Morning
Within 1 hr after the colonoscopy procedure
No
Shibu Varughese, M.D.
Principal Investigator
Cleveland Clinic Florida
United States: Institutional Review Board
CCFL-8964
NCT00687830
February 2008
November 2009
Name | Location |
---|---|
Cleveland Clinic Florida | Weston, Florida 33331 |