Mediastinal Microdialysis in Early Diagnosis of Anastomotic Leakage After Resection for Esophageal Cancer: Preliminary Results
Patients undergoing oesophageal or cardia resection for cancer are monitored by mediastinal
microdialysis during the postoperative period. Subcutaneous microdialysis serves as a
control. Samples are collected every 4-hour. Samples will be analyzed continuously but the
results will not be included in the clinical evaluation of the patient.
A total of 30 patients will be included in this pilot study. The results of the mediastinal
microdialyses will be compared with the clinical course in each patient. The results form
the uncomplicated courses will be used to define the normal variations in mediastinal
microdialysis. This will be compared to results from patients with various complications.
Observational Model: Case Control, Time Perspective: Prospective
Niels Qvist, Professor
Department of Surgery
Denmark: Ethics Committee