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Observational Study of Skin Erythema by Spectrophotometer, and UV Exposure With Viospore Ultraviolet Monitors at Extreme Altitude (Mt. Everest, North Side)


N/A
N/A
N/A
Not Enrolling
Both
Altitude, Ultraviolet Rays, Antioxidants, Oxidative Stress, Erythema

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Trial Information

Observational Study of Skin Erythema by Spectrophotometer, and UV Exposure With Viospore Ultraviolet Monitors at Extreme Altitude (Mt. Everest, North Side)


The literature widely acknowledges the deleterious effects of UV radiation on skin health,
via production of oxidative free radicals. Consequently, there have been numerous studies on
the potential dermatological/anti-carcinogenic benefits of anti-oxidants, such as vitamins C
and E, melatonin, green tea, zinc, and selenium. There is, however, a limited amount of
literature on the quantity of UV exposure in high-risk settings, such as extreme altitude
and equatorial zones. Currently, there is no literature on UV exposure on Mount Everest.
Additionally, the efficacy of antioxidants (topical or systemic) has not yet been
established in this environment.

This will be an observational study where the principal investigator will collect
accumulated ultraviolet exposure at different extreme altitudes during a 6 week period of a
summit expedition on the north side of Mt. Everest. Included in the data collection will be
patient demographics, time, altitude, temperature, use of anti-oxidants, sunscreen
(weighed), and skin erythema (spectophotometer).


Inclusion Criteria:



- Participants part of the expedition who are willing to wear the monitor, and disclose
information of diet/antioxidant supplements and topical sunblock.

Exclusion Criteria:

- Participants who are unwilling to carry the UV monitor or disclose their demographics

Type of Study:

Observational

Study Design:

Observational Model: Ecologic or Community, Time Perspective: Prospective

Principal Investigator

Ivy S Cheng, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Sunnybrook Hospital Emergency Department

Authority:

Canada: Ethics Review Committee

Study ID:

005-2007

NCT ID:

NCT00685438

Start Date:

April 2007

Completion Date:

June 2007

Related Keywords:

  • Altitude
  • Ultraviolet Rays
  • Antioxidants
  • Oxidative Stress
  • Erythema
  • Environmental Medicine
  • Altitude
  • Ultraviolet Rays
  • Antioxidants
  • Oxidative Stress
  • Erythema
  • Erythema

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