Observational Study of Skin Erythema by Spectrophotometer, and UV Exposure With Viospore Ultraviolet Monitors at Extreme Altitude (Mt. Everest, North Side)
The literature widely acknowledges the deleterious effects of UV radiation on skin health,
via production of oxidative free radicals. Consequently, there have been numerous studies on
the potential dermatological/anti-carcinogenic benefits of anti-oxidants, such as vitamins C
and E, melatonin, green tea, zinc, and selenium. There is, however, a limited amount of
literature on the quantity of UV exposure in high-risk settings, such as extreme altitude
and equatorial zones. Currently, there is no literature on UV exposure on Mount Everest.
Additionally, the efficacy of antioxidants (topical or systemic) has not yet been
established in this environment.
This will be an observational study where the principal investigator will collect
accumulated ultraviolet exposure at different extreme altitudes during a 6 week period of a
summit expedition on the north side of Mt. Everest. Included in the data collection will be
patient demographics, time, altitude, temperature, use of anti-oxidants, sunscreen
(weighed), and skin erythema (spectophotometer).
Observational
Observational Model: Ecologic or Community, Time Perspective: Prospective
Ivy S Cheng, MD
Principal Investigator
Sunnybrook Hospital Emergency Department
Canada: Ethics Review Committee
005-2007
NCT00685438
April 2007
June 2007
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