Trial Information

Characterizing the Perioperative Kinetics of Reactive Hyperemia Using Noninvasive Digital Thermal Monitoring: an Observational Study of a Surrogate Marker of Endothelial Function

The Endothelial Function Test:

To perform an endothelial function test, your temperature will be taken using your fingertip
on both hands using the Vendy's-DTM machine. The Vendy's-DTM machine uses small sleeves that
fit over your fingertips to take your temperature. After your temperature is taken, your
right arm will be placed in a standard blood pressure cuff. After the cuff is inflated for 2
minutes, your temperature will be taken again from the same fingertip. The difference of
temperatures before and after inflation may be able to predict endothelial complications,
such as lung function, heart failure and heart attack.

This test will be performed within 20 days before your scheduled surgery, when surgery
begins (at the time of incision), every hour during surgery and then 1, 2, 3, and 5 days
after your surgery.

Follow-up:

You will be called to collect information about your overall health at 30 days and 1 year
after surgery. The phone call will last about 30 minutes.

Length of Study:

You will be off study after the second phone call.

This is an investigational study. Up to 60 patients will take part in this study. All will
be enrolled at M. D. Anderson.