Beta-glucan's Effect on Cetuximab Induced Cytotoxicity in Non-Small Cell Lung Cancer
Beta-glucan (Imucell WGP) is an over-the-counter dietary supplement that enhances the body's
immune system. Imucell WGP is extracted from food-grade baker's yeast, which is permitted
for use in food by the U.S. Food and Drug Administration (FDA). Studies in animals have
shown that Imucell WGP helps trigger white blood cells to destroy cancer cells. Other
animal studies combining Imucell WGP with anti-cancer medications have shown greater tumor
regression and tumor-free survival.
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science
blood specimens will be obtained to examine the ability of beta-glucan to prime neutrophils CR3 and test the cytotoxicity of the primed neutrophils.
pre-treatment and post-treatment
Goetz H Kloecker, MD
James Graham Brown Cancer Center
United States: Institutional Review Board
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