Immuno-embolization of Hepatic Artery With Granulocyte-macrophage Colony Stimulating Factor (GM-CSF)
Patients with uveal melanoma metastatic to the liver will be treated with embolization of
the hepatic artery every 4 weeks. GM-CSF (granulocyte-macrophage colony simulating factor)
or normal saline will be injected into one of the liver arteries with an oily contrast dye,
Ethiodol. This is followed by blockage of the artery with small pieces of gelatin sponge
(embolization).
Interventional
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Determine whether immuno-embolization of the liver with GM-CSF produces clinical benefit in patients with metastatic uveal melanoma
Every 8 weeks
No
Takami Sato, M.D., Ph.D.
Principal Investigator
Thomas Jefferson University
United States: Food and Drug Administration
04F.445
NCT00661622
October 2004
June 2012
Name | Location |
---|---|
Thomas Jefferson University | Philadelphia, Pennsylvania 19107-6541 |