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Ovarian Conservation: Long-Term Health Outcomes From the Nurse's Health Study.


N/A
30 Years
55 Years
Not Enrolling
Female
Coronary Heart Disease, Stroke, Breast Cancer, Ovarian Cancer, Cancer, Hip Fracture, Death

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Trial Information

Ovarian Conservation: Long-Term Health Outcomes From the Nurse's Health Study.


We are conducting a prospective, observational study of 32,175 women participants of the
Nurse's Health Study who had a hysterectomy with or without removal of both ovaries. We are
evaluating mortality and morbidity due to the following conditions: coronary heart disease,
stroke, breast cancer, ovarian cancer, other cancer, hip fracture and death from all causes.


Inclusion Criteria:



- Women who had hysterectomies were classified into simple hysterectomy or hysterectomy
with both ovaries removed.

Exclusion Criteria:

- Evidence of cancer, coronary heart disease (MI or Angina Pectoris), stroke, or hip
fracture before entering the study were excluded. Cancer as an indication for
hysterectomy also excluded.

- Women reporting unilateral oophorectomy, unknown oophorectomy status, unknown age of
hysterectomy, or those who had oophorectomy before hysterectomy were excluded.

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Prospective

Outcome Measure:

mortality and morbidity due to the following conditions: coronary heart disease, stroke, breast cancer, ovarian cancer, other cancer, hip fracture and death from all causes.

Outcome Time Frame:

28 years

Safety Issue:

No

Principal Investigator

William H Parker, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

John Wayne Cancer Institute

Authority:

United States: Institutional Review Board

Study ID:

PARW-OVCONS-0307

NCT ID:

NCT00655447

Start Date:

January 1980

Completion Date:

June 2004

Related Keywords:

  • Coronary Heart Disease
  • Stroke
  • Breast Cancer
  • Ovarian Cancer
  • Cancer
  • Hip Fracture
  • Death
  • oophorectomy
  • ovarian conservation
  • stroke
  • breast cancer
  • ovarian cancer
  • other cancer
  • hip fracture
  • Breast Neoplasms
  • Coronary Artery Disease
  • Myocardial Ischemia
  • Coronary Disease
  • Fractures, Bone
  • Heart Diseases
  • Hip Fractures
  • Ovarian Neoplasms
  • Stroke

Name

Location

Parker, Rosenman, Rodi Gynecology GroupSanta Monica, California  90401