Inclusion Criteria:

- Female

- Invasive carcinoma of the breast confirmed by needle biopsy or final
pathological evaluation of the surgical specimen

- Breast cancer Stage I, II or IIIa

- ER and/or PR+

- No evidence of metastatic disease

- Post-menopausal

- May or may not have received adjuvant or neoadjuvant chemotherapy

- Bilateral infiltrating carcinoma are eligible

Exclusion Criteria:

- Men not eligible

- Other malignancies

- Patients who have received neoadjuvant or adjuvant endocrine therapy with tamoxifen
or an aromatase inhibitor

- Ongoing treatment with any sex hormonal therapy (these patients are eligible if this
therapy is discontinued prior to entry)

- Therapy with hormonal agent such as raloxifene for osteoporosis

- Patients receiving glucocorticoids

- Psychiatric or addictive disorders

- Inability to read English or French