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The Prognostic Impact of Extracapsular Lymph Node Involvement (ECLNI) in Ductal Pancreatic Adenocarcinoma (DPAC).


N/A
N/A
N/A
Not Enrolling
Both
Pancreatic Neoplasms, Pancreatic Adenocarcinoma

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Trial Information

The Prognostic Impact of Extracapsular Lymph Node Involvement (ECLNI) in Ductal Pancreatic Adenocarcinoma (DPAC).


Presence and extent of extracapsular lymph node involvement (ECLNI) will be scored by
reviewing all original pathological slides.

ECLNI is defined as metastatic adenocarcinoma extending through the nodal capsule into the
perinodal fatty tissue.

Observers: 1 experienced board-certified GI pathologist, blinded for follow-up results.

Follow-up data are obtained by reviewing patients charts and by a telephone survey of the
patient's GP/gastroenterologist in November 2007.

Statistical analysis:

- Common closing date: 1/11/2007

- Kaplan-Meier survival analysis (Log-Rank, Wilcoxon)

- Cox logistic regression (uni/multivariate)


Inclusion Criteria:



- DPAC

- Primary resection

Exclusion Criteria:

- Positive section margins

- non DPAC, other tumor

- Postoperative mortality

- Neoadjuvant chemo/radiotherapy

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Retrospective

Outcome Measure:

Overall cancer-specific survival

Outcome Time Frame:

11/2007

Safety Issue:

No

Principal Investigator

Baki Topal, MD, PhD

Investigator Role:

Study Director

Investigator Affiliation:

Catholic University Leuven (KULeuven), Belgium

Authority:

Belgium: Ministry of Social Affairs, Public Health and the Environment

Study ID:

ECLNI DPAC

NCT ID:

NCT00644254

Start Date:

October 2007

Completion Date:

March 2008

Related Keywords:

  • Pancreatic Neoplasms
  • Pancreatic Adenocarcinoma
  • Prognosis
  • Extracapsular lymph node involvement
  • Adenocarcinoma
  • Adenocarcinoma, Mucinous
  • Neoplasms
  • Pancreatic Neoplasms

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