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A Safety and Efficacy Trial Evaluating the Use of Apixaban in the Treatment of Symptomatic Deep Vein Thrombosis and Pulmonary Embolism

Phase 3
18 Years
Open (Enrolling)
Venous Thrombosis

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Trial Information

A Safety and Efficacy Trial Evaluating the Use of Apixaban in the Treatment of Symptomatic Deep Vein Thrombosis and Pulmonary Embolism

Inclusion Criteria:

- Men and women ≥ 18 years of age

- Clinical diagnosis of DVT or PE

Exclusion Criteria:

- Contraindications for enoxaparin or warfarin

- Active bleeding or high risk for serious bleeding

- Short life expectancy

- Uncontrolled high blood pressure

- Significantly impaired kidney or liver function

Type of Study:


Study Design:

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Outcome Measure:

Venous thromboembolic recurrence or death

Outcome Time Frame:

upon occurrence during study treatment

Safety Issue:


Principal Investigator

Bristol-Myers Squibb

Investigator Role:

Study Director

Investigator Affiliation:

Bristol-Myers Squibb


United States: Institutional Review Board

Study ID:




Start Date:

July 2008

Completion Date:

March 2013

Related Keywords:

  • Venous Thrombosis
  • Embolism
  • Pulmonary Embolism
  • Thrombosis
  • Venous Thrombosis
  • Venous Thromboembolism



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