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A Safety and Efficacy Trial Evaluating the Use of Apixaban in the Treatment of Symptomatic Deep Vein Thrombosis and Pulmonary Embolism


Phase 3
18 Years
N/A
Open (Enrolling)
Both
Venous Thrombosis

Thank you

Trial Information

A Safety and Efficacy Trial Evaluating the Use of Apixaban in the Treatment of Symptomatic Deep Vein Thrombosis and Pulmonary Embolism


Inclusion Criteria:



- Men and women ≥ 18 years of age

- Clinical diagnosis of DVT or PE

Exclusion Criteria:

- Contraindications for enoxaparin or warfarin

- Active bleeding or high risk for serious bleeding

- Short life expectancy

- Uncontrolled high blood pressure

- Significantly impaired kidney or liver function

Type of Study:

Interventional

Study Design:

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Outcome Measure:

Venous thromboembolic recurrence or death

Outcome Time Frame:

upon occurrence during study treatment

Safety Issue:

Yes

Principal Investigator

Bristol-Myers Squibb

Investigator Role:

Study Director

Investigator Affiliation:

Bristol-Myers Squibb

Authority:

United States: Institutional Review Board

Study ID:

CV185-056

NCT ID:

NCT00643201

Start Date:

July 2008

Completion Date:

March 2013

Related Keywords:

  • Venous Thrombosis
  • Embolism
  • Pulmonary Embolism
  • Thrombosis
  • Venous Thrombosis
  • Venous Thromboembolism

Name

Location

Stanford University Medical CenterStanford, California  94305-5408
Washington University School of MedicineSaint Louis, Missouri  63110
Hurley Medical CenterFlint, Michigan  48503
Morristown Memorial HospitalMorristown, New Jersey  07962-1956
Henry Ford HospitalDetroit, Michigan  48202
Bridgeport HospitalBridgeport, Connecticut  06610
New York Medical CollegeValhalla, New York  10595
University of Arkansas for Medical SciencesLittle Rock, Arkansas  72205
Carolinas Medical CenterCharlotte, North Carolina  28232-2861
Greenville Hospital SystemGreenville, South Carolina  29605
Rex HealthcareRaleigh, North Carolina  27607
Creighton University Medical CenterOmaha, Nebraska  68131-2197
Anne Arundel Medical CenterAnnapolis, Maryland  21401
Duke University Medical CenterDurham, North Carolina  27710
University of California, Davis Medical CenterSacramento, California  
Oregon Health Science UniversityPortland, Oregon  97239
Great Falls Clinic, LLPGreat Falls, Montana  59405
Penn State Milton S. Hershey Medical CenterHershey, Pennsylvania  17033
Cancer Care Centers of South TexasSan Antonio, Texas  78229
Richmond University Medical CenterStaten Island, New York  10310-1699
Veterans Affairs Medical CenterKansas City, Missouri  64128
University of Utah Medical CenterSalt Lake City, Utah  84132
George Washington University Medical Faculty AssociatesWashington, District of Columbia  20037
Atlanta Institute For Medical Research, IncDecatur, Georgia  30030
Internal Medical Associates Of Grand Island, P.CGrand Island, Nebraska  68803
Holston Medical GroupBristol, Tennessee  37620
Fort Smith Lung CenterFort Smith, Arkansas  72901
Research Alliance, Inc.Clearwater, Florida  33756
Infectious Disease Of Indiana PscCarmel, Indiana  46032
University Of Missouri-ColumbiaColumbia, Missouri  65212
Mercury Street Medical Group, PllcButte, Montana  59701
Beaver Medical GroupHighland, California  92346
Cleveland Clinic FloridaWeston, Florida  33331
West Suburban Medical CenterOak Park, Illinois  60302
Alabama Clinical Therapeutics, LlcBirmingham, Alabama  35235
Horizon Research Group, Inc.Mobile, Alabama  36608
University Of California San Francisco-FresnoFresno, California  93701
Chest Medicine & Critical Care Medical Gr. Inc.San Diego, California  92123
Harbor Ucla Medical CenterTorrance, California  90509
New West PhysiciansGolden, Colorado  80401
Drogue Medical, LlcWheat Ridge, Colorado  80033
Dept Of Internal Med, Sect Of Pulmonary & Critical Care MedNew Haven, Connecticut  06510
Bay Pines Va Healthcare SystemsBay Pines, Florida  33744
Daniel G. Lorch, Jr, Md, CpiBrandon, Florida  33511
River City Clinical ResearchJacksonville, Florida  32207
Pasadena Center For Medical ResearchSt. Petersburg, Florida  33707
Tampa Clinical ResearchTampa, Florida  33624
Office Of Michele S. Maholtz MdVero Beach, Florida  32960
Atlanta Pulmonary GroupAtlanta, Georgia  30342
Chatham HospitalistsSavannah, Georgia  31405
Gateway Cardiology. P.CJerseyville, Illinois  62052
Heartland Vascular Medicine And SurgeryWindsor Heights, Iowa  50324
Kentucky Lung ClinicHazard, Kentucky  41701
Univ. Of Kentucky Dept. Of SurgeryLexington, Kentucky  40536
Research Integrity, LlcOwensboro, Kentucky  42303
Pen Bay Medical CenterRockport, Maine  04856
Medstar Research Health InstituteBaltimore, Maryland  21237
R Adams Cowley Shock Trauma CenterBaltimore, Maryland  21201
Mississippi Medical Research, LlcPicayune, Mississippi  39466
Mercy Hospital St.LouisSt. Louis, Missouri  63141
Pulmonary & Critical Care Services, PcAlbany, New York  12205
Kaleida Health SystemBuffalo, New York  14209
Piedmont Healthcare/ResearchStatesville, North Carolina  28625
Wilmington Medical ResearchWilmington, North Carolina  28401
Clinical Trials Of America, Inc.Winston Salem, North Carolina  27103
Altru Health System ClinicGrand Forks, North Dakota  58201
Huron HospitalCleveland, Ohio  44112
Remington Davis Inc.Columbus, Ohio  43215
Palmetto Clinical ResearchSummerville, South Carolina  29485
Kore Cv ResearchJackson, Tennessee  38305
Lake Washington Vascular, PllcBellevue, Washington  98004
Franciscan Research CenterTacoma, Washington  98405