Clinical Implementation and Evaluation of MR Spectroscopy for Breast Cancer Detection
Recent in vivo studies have reported successful use of 1H and 31P MRS in differentiating
between benign and malignant tumors in breast tissue. These studies demonstrated an
increase in the choline metabolite peak that reflects an increase in choline-containing
metabolites in 70-80% of breast carcinomas, as compared to 14-18% of benign breast
tumors.The objectives would be to determine sensitivity/specificity of MRS in the context of
breast CA, We will use normal volunteers to test software and to develop and optimize MR
scan sequences prior to or during the testing of target subjects with suspicious breast
lesion.
Observational
Observational Model: Case-Only, Time Perspective: Prospective
Andrzej Krol, PhD
Principal Investigator
State University of New York - Upstate Medical University
United States: Institutional Review Board
SUNYUMU 4909
NCT00639171
November 2003
Name | Location |
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SUNY Upstate Medical University | Syracuse, New York 13210 |