Rectal Cancer Trial On Defunctioning Stoma
The assumption that a defunctioning loop stoma reduces symptomatic anastomotic leakage from
15% to 7.5%, with a level of statistical significance of 5% and a statistical power of 80%,
requires randomization of 220 patients.
Time Perspective: Prospective
Symptomatic anastomotic leakage following low anterior resection of the rectum for cancer with and without a defunctioning stoma. Anorectal function after one and five years without defunctioning stoma.
30 days, one year and five years.
Rune Sjödahl, MD, PhD
Department of Surgery, Linköping University Hospital
Sweden: Institutional Review Board