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Early Screening of Hepatocellular Carcinoma in Cirrhotic Patients: a Prospective Study


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Open (Enrolling)
Both
Cirrhosis, Hepatocellular Carcinoma

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Trial Information

Early Screening of Hepatocellular Carcinoma in Cirrhotic Patients: a Prospective Study


Well-diagnosed consecutive patients with cirrhosis were enrolled through a designed
questionnaire to obtain basic information about gender, age, etiology of cirrhosis,
conventional liver function tests, serum AFP level, education level, substance use including
smoking, alcohol drinking, betel quid chewing, history of familial HCC, etc. Then the
patients was followed by periodic abdominal sonography examination and determination of AFP
and liver function. If AFP elevated or liver nodule appears, effort to diagnose HCC will be
performed.If HCC was performed, the survival will be followed-up.


Inclusion Criteria:



- Image diagnosis or biochemical diagnosis or presence of portal hypertension

Exclusion Criteria:

- Presence of hepatocellular carcinoma

Type of Study:

Observational

Study Design:

Observational Model: Case-Only, Time Perspective: Prospective

Outcome Measure:

development of hepatocellular carcinoma

Outcome Time Frame:

during observation

Safety Issue:

Yes

Principal Investigator

Jung-Fa Tsai, M.D., Ph.D.

Investigator Role:

Principal Investigator

Investigator Affiliation:

Kaohsiung Medical University

Authority:

Taiwan: Department of Health

Study ID:

KMUH-IRB-960012

NCT ID:

NCT00629421

Start Date:

January 2001

Completion Date:

December 2013

Related Keywords:

  • Cirrhosis
  • Hepatocellular Carcinoma
  • Carcinoma
  • Liver Cirrhosis
  • Fibrosis
  • Carcinoma, Hepatocellular

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