Inclusion Criteria:

- Histologically or cytologically documented benign thyroid nodule, or cold thyroid
nodule as documented by thyroid scan.

- Patient has been evaluated by endocrinology and endocrine surgery and has been deemed
suitable candidate for procedure.

- The patient's nodule(s) size and number must be no larger than 5cm and a maximum of 3
nodules, respectively.

- All nodules must be greater than 1cm from the expected location of the recurrent
laryngeal and vagus nerves determined under ultrasound.

- Required initial laboratory values: T3, T4. TSH, and Thyroglobulin (for treated
metastatic lymph nodes)

- All patients must understand and sign a study-specific informed consent.

Exclusion Criteria:

- Thyroid mass in contact with trachea or esophagus.

- Uncontrolled coagulopathy or bleeding diathesis that cannot be corrected with FFP and
platelets prior to procedure. (Platelets must be ≥ 70,000/ul.)

- Aspirin and nonsteroidal anti-inflammatory medications, antiplatelet medications, or
warfarin must be discontinued prior to the procedure for a time period that is
appropriate given the drug half-life and the drugs known antiplatelet activity (e.g.
aspirin for 7 days and ibuprofen 24 hours). Low molecular weight heparin preparations
must be discontinued 24 hours prior to procedure.