Inclusion Criteria

Inclusion criteria:

- The 38 patients from the SUNY Upstate Medical Center Pediatric Oncology Long-term
Survivor Clinic who were subjects in the original Georg Fund supported study will
comprise the patient population if they are locatable and willing to participate.

- Patients must be less than 40 years of age to participate.

Exclusion criteria:

- Patients who have received interval treatment for Acute Lymphocytic Leukemia (ALL)
and those who have received subsequent cranial irradiation or total body irradiation
(groups already known to be at high risk for osteoporosis) will be excluded. These
would have had to have occurred in the interval since the original study, as these
were also exclusion criteria for that study. In addition, any patient who received
interval non-autologous bone marrow transplant will be excluded, as these patients
may have graft versus host disease (also known to be associated with osteopenia).