Trial Information

Lipiodol Demarcation of the Bladder Tumour in Adaptive Image-Guided Radiotherapy: A Pilot Study. (Danish: Lipiodol Til Markering af blæretumoren i Forbindelse Med Adaptiv Billedvejledt strålebehandling: Et Pilotstudie.)

To exploit the potential of modern Radiotherapy (RT), it is important to localize and follow
the target precisely during treatment. Since the bladder tumour can usually not be
identified on conventional CT-scan, a fiducial or contrast marking system is warranted.

The iodized oil, Lipiodol is a well-known contrast media used mainly for lymphography and
Hysterosalpingography. Local Lipiodol demarcation has been used for localisation of tumours
in the lung, prostate and seminal vesicles visualised on Computed Tomography (CT) and
fluoroscopy.

Purpose: To evaluate the feasibility of tumour demarcation using the contrast agent Lipiodol
in adaptive Image-guided RT of bladder cancer. Visibility on CT, Cone-Beam CT, MRI and
on-board imaging will be evaluated.