Prospective Randomized Trial of Laparoscopic Versus Open Liver Resection for Patients With Hepatocellular Carcinoma
Advantages and disadvantages of the laparoscopic compared with the open approach for liver
resections
1. Advantages 1) Less postoperative ascites production 2) Reduced postoperative pain 3)
Feasible in selected cirrhotics who have contraindications to open surgery 4) Less
intra-abdominal adhesions (easier salvage transplantation) 5) Shorter recovery time 6)
Shorter length of stay 7) Reduced financial cost
2. Disadvantages 1) No manual palpation or exploration of the liver parenchyma possible
(with the pure laparoscopic approach) 2) High demand in surgical skill (especially
major resections)
Interventional
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Recurrence rate
2 years after operation
Yes
Ho-Seong Han, MD, PhD
Study Chair
Department of Surgery, Seoul National University Bundang Hospital
Korea: Food and Drug Administration
SNUBH-GS-HBP1
NCT00606385
December 2007
December 2016
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