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A Pilot Study to Assess the Feasibility of Cone Beam CT to Localize Liver Metastases Immediately Prior to Radiotherapy


N/A
18 Years
95 Years
Not Enrolling
Both
Localize Liver Metastases

Thank you

Trial Information

A Pilot Study to Assess the Feasibility of Cone Beam CT to Localize Liver Metastases Immediately Prior to Radiotherapy


Inclusion Criteria:



- Age > than or equal to 18 years

- KPS > than or equal to 80

- Able to tolerate immobilization cradle positioning

- Able to give informed consent

- Histologically confirmed diagnosis of solid tumor malignancy

- Liver metastases visualized on CT imaging

Exclusion Criteria:

- Lymphoid primary histology (lymphoma/leukemia)

- Allergic reaction to intravenous CT contrast

- Liver function tests (AST, ALT, Bilirubin) > 2.0 x normal

- Abnormal kidney function (serum creatinine > 1.5)

- INR > 2.0, Platelet count <70.000.

- Marker seed placement not possible

- > 5mm excursion after abdominal compression

Type of Study:

Interventional

Study Design:

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Outcome Measure:

To gather the data necessary to assess the feasibility of using a new imaging technique called "cone beam imaging" to localize a liver tumor immediately prior to external beam radiotherapy.

Outcome Time Frame:

conclusion of study

Safety Issue:

No

Principal Investigator

Yoshiya Yamada, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Memorial Sloan-Kettering Cancer Center

Authority:

United States: Institutional Review Board

Study ID:

05-129

NCT ID:

NCT00600613

Start Date:

January 2006

Completion Date:

October 2010

Related Keywords:

  • Localize Liver Metastases
  • Radiation Therapy
  • Neoplasm Metastasis
  • Neoplasms, Second Primary
  • Liver Neoplasms

Name

Location
Memorial Sloan Kettering Cancer Center New York, New York  10021