Inclusion Criteria:

- Cases will be eligible for inclusion if:

- They have been diagnosed with a lung cancer or have had previous surgical treatment
for their lung cancer and have smoked fewer than 100 cigarettes in their lifetime,
are/were not regular cigar or pipe smokers, and

- They have had no prior chemotherapy or radiation treatment within the last year
(Exception: genotyping analysis/screening can be performed on specimens from
individuals who had chemo/radiation treatment within the last year as germline DNA
will not be affected)

- They speak and read English

- They understand and agree to sign informed consent, and

- They agree to give us a blood sample, and

- They agree to complete the study questionnaire, and

- They agree to have their pathology information reviewed by study personnel.

- Controls will be eligible for inclusion if:

- They have not been diagnosed with any type of cancer, exclusive of nonmelanoma skin
cancer and have smoked fewer than 100 cigarettes in their lifetime, are/were not
regular cigar or pipe smokers, and

- They speak and read English

- They understand and agree to sign informed consent, and

- They agree to give us a blood sample, and

- They agree to complete the study questionnaire.

Exclusion Criteria:

- Subjects who do not meet the inclusion criteria for either the case or control groups
will not be eligible for this study.

- All individuals who otherwise meet the eligibility requirements above, but who have
had chemotherapy or radiation therapy within 1 year of evaluation will be excluded
(Exception: genotyping analysis/screening can be performed on specimens from
individuals who had chemo/radiation treatment within the last year as germline DNA
will not be affected).