A Comparative Trial of Over-the-counter Dry Mouth Remedies for Dry Mouth After Radiation to the Head and Neck
Xerostomia (dry mouth) is the most common late complication of radiation therapy for head
and neck cancers. When patients are cured or survive for several years, xerostomia often
becomes quite bothersome; it affects their quality of life. This study compares the
effectiveness of seven over-the-counter remedies, 2 rinses, 3 sprays and 2 chewing gums. A
computer program will make random assignments so that the patient nor the physician will
choose the order in which the products are tried. The remedies will be used for one week
each and at the end of each period the patient will fill out a questionaire.
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
The effectiveness of seven over-the-counter remedies for dry mouth as determined by amount of saliva output and a brief questionaire.
Greg Krempl, MD
University of Oklahoma
United States: Institutional Review Board
|University of Oklahoma Health Sciences Center||Oklahoma City, Oklahoma 73104|