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Preoperative Oncogeriatric Assessment for Thoracic Malignancies


N/A
70 Years
N/A
Open (Enrolling by invite only)
Both
Thoracic Neoplasms, Lung Neoplasms, Esophagus Neoplasms, Pleural Neoplasms, Thymus Neoplasms

Thank you

Trial Information

Preoperative Oncogeriatric Assessment for Thoracic Malignancies


Our proposed TOGA wil consist of portions of the PACE and some additional screening tools,
and will be applied prospectively to all patients 70 years old and above seen in the UWCCC
for a thoracic oncology surgery. Residents of nursing homes and assisted living facilities
will be eligible for this study if they are thought to be appropriate surgical candidates;
other institutionalized patients will not. The preoperative TOGA will be performed by either
Drs. Weigel, Maloney, LoConte or Traynor or P.A. Block. The TOGA includes parts of the
PACE, involving assessment of co-morbid illness, Activities of Daily Living [ADL],
Instrumental Activities of Daily Living [IADL], Geriatric Depression Screen [GDS], Brief
Fatigue Inventory [BFI], Eastern Cooperative Oncology Group/Zubrod Performance Status [PS],
Mini Mental State Exam (MMSE), in addition to an American Society of Anesthesiologists
Score[ASA] and mini nutritional assessment (MNA), which were not done in the PACE. The TOGA
should take up to 25 minutes to complete (Audisio, 2006), and will be done at only one time
preoperativelOur hypothesis is that this novel, preoperative Thoracic Onco Geriatric
Assessment (TOGA) will serve to predict outcomes for older patients going though thoracic
oncology surgery, and thus will enhance geriatric patient care through the development of
concise, validated, preoperative risk stratification.

Our hypothesis is that this abbreviated geriatric screening tool will be a better predictor
for surgical and oncologic complications after surgery than performance status alone (which
is currently the only measure of fitness used in routine oncology care). In addition, we
predict that parts of the TOGA, specifically the instrumental activites of daily living
score (IADL), mini nutritional assessment (MNA) and the brief fatigue inventory (BFI), will
be the strongest predictor(s) of outcomes in our thoracic surgery population. The outcomes
data we generate will also be important in quality improvement and standardization of
preoperative risk assessment for elderly patients with thoracic malignancies.


Inclusion Criteria:



- Patients 70 years old and above seen in the UWCCC for a thoracic oncology surgery.

- Residents of nursing homes and assisted living facilities will be eligible for this
study if they are thought to be appropriate surgical candidates.

Exclusion Criteria:

- Institutionalized deemed not to be appropriate.

- Prisoners

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Prospective

Outcome Measure:

Morbidity (Cardiac, pulmonary, infectous, etc.) and Mortality in Cohort

Outcome Time Frame:

30days

Safety Issue:

No

Principal Investigator

Tracey L Weigel, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

University of Wisconsin Dept of Surgery CardioThoracic Division

Authority:

United States: Institutional Review Board

Study ID:

M-2006-0352

NCT ID:

NCT00591981

Start Date:

August 2007

Completion Date:

December 2009

Related Keywords:

  • Thoracic Neoplasms
  • Lung Neoplasms
  • Esophagus Neoplasms
  • Pleural Neoplasms
  • Thymus Neoplasms
  • Geriatric
  • Thoracic
  • neoplasm
  • (Patients over 70 years of age) Geriatric oncology patients with thoracic neoplasms of the lung, esophagus, pleura and thymus.
  • Neoplasms
  • Esophageal Neoplasms
  • Lung Neoplasms
  • Pleural Neoplasms
  • Thoracic Neoplasms
  • Thymus Neoplasms

Name

Location

University of Wisconsin HospitalMadison, Wisconsin  53792