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The Use of Breathing Synchronized CT and PET Scans in Radiation Therapy Treatment Planning


N/A
18 Years
N/A
Not Enrolling
Both
Lung Cancer, Non-Hodgkin's Lymphoma

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Trial Information

The Use of Breathing Synchronized CT and PET Scans in Radiation Therapy Treatment Planning


The objectives are to measure the amount of tumor motion with respiration, measure changes
in tumor definition with breathing synchronized PET compared to standard free breathing PET,
and to determine the fraction of patients whose radiation treatment plans would be modified
based on this information. Eligible patients are those receiving radiation treatment for
thoracic or liver tumors.


Inclusion Criteria:



- Age ≥ 18 years old

- Ability to sign informed consent form indicating investigative nature of this study,
in keeping with the policies of the hospital.

- Patients must have thoracic disease visible on a Chest CT scan, or liver disease
visible on a abdominal CT scan.

Exclusion Criteria:

- Pregnant women are ineligible. A pregnancy test will be performed on each fertile
premenopausal female prior to entry into the study.

- Patients with thoracic or liver disease that is not visible on CT scan

- Patients who are unable to follow directions either due to language difficulties or
hearing impairment.

- Patients who are too ill to hold their breath.

Type of Study:

Interventional

Study Design:

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Outcome Measure:

To measure the amount of tumor motion in breathing synchronized CT scans and determine the fraction of patients whose radiation treatment planning margins would be modified based on this information.

Outcome Time Frame:

2 years

Safety Issue:

No

Principal Investigator

Kenneth Rosenzweig, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Memorial Sloan-Kettering Cancer Center

Authority:

United States: Food and Drug Administration

Study ID:

00-008

NCT ID:

NCT00588328

Start Date:

March 2000

Completion Date:

May 2010

Related Keywords:

  • Lung Cancer
  • Non-Hodgkin's Lymphoma
  • Lung Neoplasms
  • Lymphoma
  • Lymphoma, Non-Hodgkin

Name

Location
Memorial Sloan-Kettering Cancer Center New York, New York  10021