Trial Information
One-Stage Ultrasound-Guided Hepatectomy for Multiple Bilobar Colorectal Metastases: a Feasible and Effective Alternative to Two-Stage Hepatectomy
Inclusion Criteria:
1. Patients presenting with resectable colorectal cancer liver metastases (CLM)
2. 4 or more lesions
3. Bilobar involvement of the liver
4. Contact or close adjacency (less than 0.5 cm) of at least one CLM with major
intrahepatic vascular structures (1st or 2nd order portal branches and/or hepatic
vein at caval confluence).
Exclusion Criteria:
1. Patients with 3 or less resectable CLM
2. Patients with 4 or more resectable CLM but nor bilobar
3. Patients with 4 or more bilobar resectable CLM without any lesion presenting
condition of point 4 of the inclusion criteria
Type of Study:
Observational
Study Design:
Observational Model: Cohort, Time Perspective: Prospective
Outcome Measure:
The primary outcome was the safety of the procedure. To this purpose we studied morbidity, mortality, amount of blood loss, rate of blood transfusions, and postoperative trend of liver function tests.
Outcome Time Frame:
30-day and 90-day postoperatively
Safety Issue:
Yes
Principal Investigator
Guido Torzilli, MD, PhD
Investigator Role:
Principal Investigator
Investigator Affiliation:
University of Milan, Istituto Clinico Humanitas - IRCCS
Authority:
Italy: Ministry of Health
Study ID:
MTX-1STAGE
NCT ID:
NCT00587756
Start Date:
September 2001
Completion Date:
December 2007
Related Keywords:
- Colorectal Cancer
- Liver Metastases
- intraoperative ultrasonography
- colorectal liver metastases
- hepatectomy
- portal vein embolization
- Liver
- Colorectal Neoplasms
- Neoplasm Metastasis
- Liver Neoplasms