Trial Information

Endoscopic Mucosal Resection in Barrett's Esophagus

Barrett's esophagus (BE) is a complication of gastroesophageal reflux disease in which the
normal squamous lining of the esophagus is replaced by specialized columnar epithelium.1
Approximately 5%-10% of patients diagnosed with BE are thought to be at risk of developing
esophageal adenocarcinoma.2 Patients with high-grade dysplasia (HGD) on biopsy are at the
greatest cancer risk³. EMR is being performed clinically in our Barrett's Esophagus Unit on
a regular basis during endoscopy for patients with Barrett's Esophagus and/or early
esophageal adenocarcinoma. There are two predominant endoscopic mucosal resection (EMR)
techniques exist using FDA approved devices - the EMR cap method using a transparent
cap/snare combination and the endoscopic variceal ligation method using a band ligator/snare
combination to resect tissue.