Know Cancer

or
forgot password

Endoscopic Mucosal Resection in Barrett's Esophagus


N/A
18 Years
N/A
Open (Enrolling)
Both
Barrett's Esophagus, Early Esophageal Adenocarcinoma

Thank you

Trial Information

Endoscopic Mucosal Resection in Barrett's Esophagus


Barrett's esophagus (BE) is a complication of gastroesophageal reflux disease in which the
normal squamous lining of the esophagus is replaced by specialized columnar epithelium.1
Approximately 5%-10% of patients diagnosed with BE are thought to be at risk of developing
esophageal adenocarcinoma.2 Patients with high-grade dysplasia (HGD) on biopsy are at the
greatest cancer riskĀ³. EMR is being performed clinically in our Barrett's Esophagus Unit on
a regular basis during endoscopy for patients with Barrett's Esophagus and/or early
esophageal adenocarcinoma. There are two predominant endoscopic mucosal resection (EMR)
techniques exist using FDA approved devices - the EMR cap method using a transparent
cap/snare combination and the endoscopic variceal ligation method using a band ligator/snare
combination to resect tissue.


Inclusion Criteria:



- Barrett's Esophagus Early Esophageal Adenocarcinoma History of Endoscopic Mucosal
Resection

Exclusion Criteria:

- NA

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Retrospective

Principal Investigator

Kenneth K Wang, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Mayo Clinic

Authority:

United States: Institutional Review Board

Study ID:

07-007063

NCT ID:

NCT00586872

Start Date:

October 2007

Completion Date:

October 2017

Related Keywords:

  • Barrett's Esophagus
  • Early Esophageal Adenocarcinoma
  • Barrett's Esophagus
  • Early Esophageal Adenocarcinoma
  • Endoscopic Mucosal Resection
  • Adenocarcinoma
  • Adenocarcinoma, Mucinous
  • Barrett Esophagus
  • Esophageal Diseases

Name

Location

Mayo ClinicRochester, Minnesota  55905