Evaluation of Change in the Lumpectomy Cavity During Radiation Therapy by Weekly Ultrasound and by Daily Ultrasound During the Radiation Boost Dose
Study participants will have weekly ultrasounds performed of the lumpectomy cavity to
determine shift and volume changed from the initial treatment-planning CT to the time of the
radiation boost (approximately 4 weeks). These ultrasounds are done prior to their weekly
doctor's appointment with Radiation Oncology.
When it is time to perform the radiation boost (when the radiation is more targeted to the
lumpectomy cavity), the ultrasound will be done daily with the participant in treatment
position. The SonArray system used for the ultrasound-driven targeting for prostate cancer
will be utilized. If the lumpectomy cavity is observed, the ultrasound suggested shifts will
be noted and compared to the shifts needed for standard clinical set up.
Once the subject has completed radiation therapy, the study participation is complete.
Observational Model: Case-Only, Time Perspective: Prospective
Determine the volume change in lumpectomy cavity during the course of external beam radiation prior to delivery of the radiation boost.
Geraldine Jacobson, MD MPH
The Department of Radiation Oncology
United States: Institutional Review Board
|The University of Iowa Hospitals & Clinics||Iowa City, Iowa 52242|