Longitudinal Assessment of Health-Related Quality of Life in Men With Localized Prostate Cancer
The intent of the protocol is to assess health-related quality-of-life (HRQOL) in men
treated for localized prostate cancer with 1 of 6 established management alternatives:
external (XRT)or interstitial radiotherapy (IRT), open radical prostatectomy (RP),
laparoscopic radical prostatectomy (LRP), combined radiotherapy and brachytherapy (Combined
RT) or watchful waiting (WW). HRQOL is an important aspect of any treatment for prostate
cancer due to the beliefs by many that cancer control rates are similar across common
modalities and HRQOL reduction from treatment is substantial (1-5). Therefore, HRQOL appears
to occupy a central role in the decision making process related to treatment selection.
Observational Model: Cohort, Time Perspective: Prospective
Assessment of temporal trends in HRQOL according to intervention group
study time points 3, 6, 9, 12, 15, 18, 24, 36, and 48 following treatment)and between 60 and 96 months.
Peter Scardino, M.D.
Memorial Sloan-Kettering Cancer Center
United States: Institutional Review Board
|Memorial Sloan-Kettering Cancer Center||New York, New York 10021|
|Memoral Sloan Kettering Cancer Center||Basking Ridge, New Jersey|
|Memorial Sloan-Kettering Cancer Center @ Suffolk||Commack, New York 11725|
|Memorial Sloan-Kettering at Mercy Medical Center||Rockville Centre, New York|
|Memoral Sloan Kettering Cancer Center@Phelps||Sleepy Hollow, New York|