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Dynamic Contrast Enhanced MRI (DCE-MRI) Diffusion Weighted MRI (DW-MRI) and Magnetic Resonance Spectroscopy (MRS) of Head and Neck Tumors


N/A
18 Years
N/A
Open (Enrolling)
Both
Head and Neck Cancer

Thank you

Trial Information

Dynamic Contrast Enhanced MRI (DCE-MRI) Diffusion Weighted MRI (DW-MRI) and Magnetic Resonance Spectroscopy (MRS) of Head and Neck Tumors


Inclusion Criteria:



- Patients with histologically proven diagnosis of head and neck cancer or patients
with tumors strongly suspicious for head and neck cancer due to clinical features or
FNA (fine needle aspiration) cytology assessment.

- Will undergo surgery or chemo-radiation treatment

- Presence of evaluable primary tumor

- Patients must be 18 years or older and have the ability to give informed consent

Exclusion Criteria:

- Claustrophobia

- Absence of evaluable primary tumor

- Known reaction to Gd-DTPA

- Pre-operative radiation to primary tumor site

- Contraindication to MRI

1. Pacemaker

2. Aneurysmal clips

3. Metal implants in field of view

4. Pregnant or nursing women

5. Age and mental status wherein he/she is unable to cooperate for MRI study

Type of Study:

Observational

Study Design:

Observational Model: Case-Only, Time Perspective: Prospective

Outcome Measure:

Identify a priori prognostic markers for head and neck cancer patients using DCE-MRI, DW-MRI and 1H-MRS data, which may help in stratifying patients into "good risk" and "poor risk" categories to improve outcome and quality of life.

Outcome Time Frame:

5 years

Safety Issue:

No

Principal Investigator

Amita Dave, PhD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Memorial Sloan-Kettering Cancer Center

Authority:

United States: Food and Drug Administration

Study ID:

06-007

NCT ID:

NCT00581906

Start Date:

February 2006

Completion Date:

February 2014

Related Keywords:

  • Head and Neck Cancer
  • Head and Neck Cancer
  • Head Cancer
  • Neck Cancer
  • Dynamic Contrast Enhanced MRI
  • Magnetic Resonance Spectroscopy (MRS)
  • Diffusion Weighted MRI (DW-MRI)
  • 06-007
  • Head and Neck Neoplasms

Name

Location
Memorial Sloan-Kettering Cancer Center New York, New York  10021