Trial Information

Optical Clearing of the Skin in Conjunction With Laser Treatments

The researchers expect that application of the optical clearing agent for treatment of
benign vascular lesions, tattoos, nevus of Ota, hypertrichosis, scars, acne and sebaceous
hyperplasia will result in

1. decreased reflectance of the predominant color from the surface of skin (decreased red
light scattering in case of benign vascular lesions, etc) as compared to the control
group.

2. greater Optical Coherence Tomography (OCT- a non-invasive light based imaging method)
imaging depth as compared to the control group.

3. greater improvement in the treatment outcome (decrease in the erythema index following
PDL treatment of vascular lesions as compared to the PDL alone group; improved
lightening of the tattoo or nevus of Ota as compared to the laser treatment alone
group; significant decrease in hair re-growth as compared to laser treatment alone in
patients seeking hair removal; greater improvement of scars, acne and sebaceous
hyperplasia).