Impact of Biliary Drainage on Quality Of Life in Patients With Malignant Biliary Obstruction
Malignant biliary obstruction (MBO) may arise in patients with cholangiocarcinoma,
pancreatic carcinoma, primary gallbladder carcinoma, hepatocellular carcinoma, or metastatic
disease to the liver or portal lymph nodes. MBO is often accompanied by significant symptoms
that may result in impairment of health-related quality of life (HRQL), including pruritus,
fever, nutritional deficits, abdominal pain, nausea and vomiting, and fatigue. Approaches to
the relief of MBO include surgical bypass and/or resection, percutaneous drainage with or
without biliary stenting, or endoscopic stenting. The non surgical procedures may be done
prior to attempted curative resection or for palliation in individuals with unresectable or
recurrent disease.
Observational
Observational Model: Cohort, Time Perspective: Prospective
To determine how surgical or percutaneous drainage affects HRQL scores in patients with MBO, and to determine if these changes are sustained or change over time.
conclusion of the study
No
Piera Robson, RN, BSN
Principal Investigator
Memorial Sloan-Kettering Cancer Center
United States: Institutional Review Board
04-036
NCT00579865
May 2005
January 2010
Name | Location |
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Memorial Sloan Kettering Cancer Center | New York, New York 10021 |