Know Cancer

or
forgot password

A Prospective Trial to Assess the Variability of Uni-Dimensional, Bi-Dimensional, and Volumetric CT Scan Measurement of Non-Small Cell Lung Cancer Tumors


N/A
18 Years
N/A
Not Enrolling
Both
Lung Cancer, Non Small Cell

Thank you

Trial Information

A Prospective Trial to Assess the Variability of Uni-Dimensional, Bi-Dimensional, and Volumetric CT Scan Measurement of Non-Small Cell Lung Cancer Tumors


Standard criteria for tumor response assessment have used uni-dimensional or bi-dimensional
measurements as a surrogate for volume determination. Modern CT scan techniques, in
combination with algorithms developed at MSKCC, allow the calculation of tumor volume. This
protocol is designed to evaluate the reproducibility of the calculated volume of pulmonary
masses on separate CT scans obtained on the same day in patients with non-small cell lung
cancer (NSCLC). Patients with NSCLC undergoing non-contrast CT scan of the chest will have a
second, non-contrast CT scan of the chest performed. Uni-dimensional, bi-dimensional, and
volume measurements for the primary NSCLC lesion will be determined on both scans and the
values compared.


Inclusion Criteria:



- Have pathologically confirmed non-small cell lung cancer

- Have measurable primary pulmonary tumors ≥ 1cm

- Have plans for a clinically indicated non-contrast CT scan of the chest

- All patients must be ≥ 18 years old

Exclusion Criteria:

- Pregnant or lactating women

Type of Study:

Observational

Study Design:

Observational Model: Case-Only, Time Perspective: Prospective

Outcome Measure:

To evaluate the reproducibility of calculated volume of pulmonary masses on separate CT scans obtained on the same day in patients with NSCLC

Outcome Time Frame:

same day, within 30 minutes

Safety Issue:

No

Principal Investigator

Mark Kris, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Memorial Sloan-Kettering Cancer Center

Authority:

United States: Institutional Review Board

Study ID:

06-149

NCT ID:

NCT00579852

Start Date:

November 2006

Completion Date:

January 2008

Related Keywords:

  • Lung Cancer
  • Non Small Cell
  • Lung
  • Carcinoma, Non-Small-Cell Lung
  • Lung Neoplasms

Name

Location

Memorial Sloan Kettering Cancer CenterNew York, New York  10021