Trial Information

A Prospective Trial to Assess the Variability of Uni-Dimensional, Bi-Dimensional, and Volumetric CT Scan Measurement of Non-Small Cell Lung Cancer Tumors

Standard criteria for tumor response assessment have used uni-dimensional or bi-dimensional
measurements as a surrogate for volume determination. Modern CT scan techniques, in
combination with algorithms developed at MSKCC, allow the calculation of tumor volume. This
protocol is designed to evaluate the reproducibility of the calculated volume of pulmonary
masses on separate CT scans obtained on the same day in patients with non-small cell lung
cancer (NSCLC). Patients with NSCLC undergoing non-contrast CT scan of the chest will have a
second, non-contrast CT scan of the chest performed. Uni-dimensional, bi-dimensional, and
volume measurements for the primary NSCLC lesion will be determined on both scans and the
values compared.