Cardiac MRI for Assessment of Cardiac Structure and Function Following Doxorubicin Based Chemotherapy for Newly Diagnosed Non-Hodgkin's Lymphoma or Hodgkin's Lymphoma
- To determine whether early myocardial structural and functional changes can be detected
using cardiac MRI in patients with newly diagnosed non-Hodgkin lymphoma or Hodgkin
lymphoma receiving doxorubicin hydrochloride-based chemotherapy.
OUTLINE: Patients undergo cardiac MRI with gadolinium contrast prior to initiation of
doxorubicin hydrochloride-based chemotherapy and 3 months after completion of six courses of
chemotherapy for non-Hodgkin lymphoma and twelve courses of chemotherapy for Hodgkin
Intervention Model: Single Group Assignment, Masking: Single Blind (Investigator), Primary Purpose: Diagnostic
Change in myocardial function and structure
cMRI will be done prior to induction of doxorubicin based chemotherapy and at three months after completion of the doxorubicin based chemotherapy regimen.
Thomas R. Porter, M.D.
University of Nebraska
United States: Institutional Review Board
|UNMC Eppley Cancer Center at the University of Nebraska Medical Center||Omaha, Nebraska 68198-7680|