Trial Information

Quality of Life and Functional Outcomes After Combined Modality Therapy for Anal Cancer: A Comparison of Conventional Versus Intensity-Modulated Radiation Therapy (ANAL0002)

The objectives of this study are three-fold. First, we would like to learn and compare the
doses of radiation received by the tumor and the normal tissues in anal cancer patients
treated with IMRT, and in those treated with conventional radiotherapy. Second, we wish to
compare the acute effects of radiation treatment in both groups of patients. Our third
objective is to evaluate the late effects of radiation treatment in both groups of patients.
The first two objectives will be studied using a retrospective analysis of patients with
anal cancer treated at Stanford University Medical Center. The third objective will require
these patients to complete and return three quality of life questionnaires.