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Application of Adenosine 5'-Triphosphate (ATP) Infusions in Palliative Home Care

Phase 3
18 Years
Not Enrolling
Cancer, Palliative Care, Survival, Quality of Life

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Trial Information

Application of Adenosine 5'-Triphosphate (ATP) Infusions in Palliative Home Care

Inclusion Criteria:

- cytologically or histologically confirmed cancer

- medical treatment options restricted to supportive care

- a life expectancy < 6 months

- World Health Organization (WHO) performance status 1 or 2

- suffering from at least one of the following complaints: fatigue, weight loss > 5%
over the last 6 months, or anorexia

Exclusion Criteria:

- symptomatic angina pectoris

- symptomatic heart failure

- any form of atrioventricular (AV) block (assessed by electrocardiogram)

- life expectancy < 4 weeks

- concurrent palliative chemotherapy

- cognitive dysfunction, and other diseases hampering adequate follow up

Type of Study:


Study Design:

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Outcome Measure:

Survival Physical restriction Fatigue Quality of life

Outcome Time Frame:

0-8 weeks

Principal Investigator

P.C. Dagnelie, PhD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Maastricht University - Department of Epidemiology


Netherlands: The Central Committee on Research Involving Human Subjects (CCMO)

Study ID:

MEC 01-092.3



Start Date:

March 2002

Completion Date:

October 2006

Related Keywords:

  • Cancer
  • Palliative Care
  • Survival
  • Quality of Life